Pharma already leads the business world in unpredictability, with billions in sales potentially riding on a few points of statistical significance in a clinical trial.[...] even within that context, a series of blockbuster medicines for hepatitis C have made for a roller-coaster ride for companies and investors.AbbVie Inc. last week threw another big curve at this market by pricing its newly FDA-approved drug Mavyret — which might be the most effective hepatitis C medicine approved yet — at a massive discount.Medicines from Johnson & Johnson, Merck & Co. Inc. and Vertex Pharmaceuticals Inc. approved within the past six years, which once booked billions in combined sales, are now essentially non-factors.After offering behind-the-scene discounts to insurance companies, pharmacy benefit managers and other payers, Mavyret’s price is actually not far from Harvoni’s, according to Bloomberg Intelligence.The real headache for Gilead — which already faces steep declines in hepatitis C drug sales because of increasing competition and the fact that many patients have been cured — lies in the fact that not all hepatitis patients or medicines are the same.AbbVie’s new drug can treat all of the major subtypes of hepatitis C. And it can cure the disease in many patients in just eight weeks.
NYS Entity Status
NYS Filing Date
MARCH 14, 2013
NYS DOS ID#
NYS Entity Type
DOMESTIC BUSINESS CORPORATION
2013 - ALWAYS APPROVED AUTO SALES INC.
AROUND THE WEB
- Abbvie’s hep C drug pricing threatens Gilead’s dominance
By Max Nisen - Tuesday Aug 8, 2017
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- Nearly 2 tons of seized ivory to be crushed in Central Park
By MARY ESCH, Associated Press - Thursday Aug 3, 2017
ALBANY, N.Y. (AP) — Nearly two tons of trinkets, statues and jewelry crafted from the tusks of at least 100 slaughtered elephants are heading for a rock crusher in New York City's Central Park to demonstrate the state's commitment to smashing the illegal ivory trade.[...] state environmental officials, who are partnering with the Wildlife Conservation Society and Tiffany & Co. for Thursday's "Ivory Crush," say no price justifies slaughtering elephants for their tusks.Last year, the U.S. Fish and Wildlife Service instituted a near-total ban on the domestic commercial ivory trade and barred sales across state lines.Since August 2014, New York law has prohibited the sale, purchase, trade or distribution of anything made from elephant or mammoth ivory or rhinoceros horn, except in limited situations with state approval.The World Wildlife Fund says the illegal wildlife trade not only threatens animal populations, but also endangers national security by funding terrorist cells.